Products

Connexin-43 antibody

Synonyms:Connexin-43 antibody, CX43 antibody, DFNB38 antibody, Gap junction alpha 1 protein antibody, GJA1 antibody, GJAL antibody, ODDD antibody
Catalogue No.:FNab10703Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
Connexin-43 antibody
Catalogue No.
FNab10703
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
gap junction protein, alpha 1, 43kDa
Alternative Names
Connexin-43 antibody, CX43 antibody, DFNB38 antibody, Gap junction alpha 1 protein antibody, GJA1 antibody, GJAL antibody, ODDD antibody
UniProt ID
P17302
Observed MW
47 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500-1:2000; IF: 1:50-1:500
Validated Images
Rat brain tissue were subjected to SDS PAGE followed by western blot with FNab10703(Connexin-43 antibody) at dilution of 1:1000
Immunofluorescent analysis of Hela cells using FNab10703(Connexin-43 antibody) at dilution of 1:50.
Background
Gap junction protein that acts as a regulator of bladder capacity. A gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. May play a critical role in the physiology of hearing by participating in the recycling of potassium to the cochlear endolymph. Negative regulator of bladder functional capacity: acts by enhancing intercellular electrical and chemical transmission, thus sensitizing bladder muscles to cholinergic neural stimuli and causing them to contract(By similarity). May play a role in cell growth inhibition through the regulation of NOV expression and localization. Plays an essential role in gap junction communication in the ventricles(By similarity).