Products
ACC1 antibody
- Product Name
- ACC1 antibody
- Catalogue No.
- FNab10685
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG2a
- Clone ID
- 9D2
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- acetyl-Coenzyme A carboxylase alpha
- Alternative Names
- ACACA Synonyms ACAC antibody, ACACA antibody, ACC antibody, ACC1 antibody, ACCA antibody, Acetyl CoA carboxylase 1 antibody
- UniProt ID
- Q13085
- Observed MW
- 270 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:2000-1:10000; IHC: 1:100-1:500
Validated Images
various lysates were subjected to SDS PAGE followed by western blot with FNab10685(ACC1 antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded human breast cancer using FNab10685(ACC1 antibody) at dilution of 1:200
- Background
- ACACA(Acetyl-CoA carboxylase 1, ACC), also named as ACAC, ACC1 and ACCA, belongs to the biotin containing enzyme family. It catalyzes the synthesis of malonyl-CoA, which is an intermediate substrate playing a pivotal role in the regulation of fatty acid metabolism and energy production. ACACA is involved in the biosynthesis of fatty acids, and malonyl-CoA produced is used as a building block to extend the chain length of fatty acids by fatty acid synthase(FAS)(PMID:19900410). It has 4 isoforms produced by alternative promoter usage with the molecular weight between 260 kDa and 270 kDa.