Products
PHF-1 antibody
- Product Name
- PHF-1 antibody
- Catalogue No.
- FNab10677
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- PHD finger protein 1
- Alternative Names
- MTF2L2 antibody, PCL1 antibody, PHD finger protein 1 antibody, PHF1 antibody, PHF2 antibody, Polycomb like protein 1 antibody, Protein PHF1 antibody
- UniProt ID
- O43189
- Observed MW
- 62-70 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:2000
Validated Images
Various lysates were subjected to SDS PAGE followed by western blot with FNab10677(PHF-1 antibody) at dilution of 1:1000
- Background
- Plant homeodomain finger protein 1 (PHF1) has a specific role in histone modification and in non-homologous end joining. It is a human homolog of the Drosophila protein Polycomb-like protein. PHF1 acts by binding to H3K36me3, a mark for transcriptional activation, and recruiting the PRC2 complex: it is however unclear whether recruitment of the PRC2 complex to H3K36me3 leads to enhance or inhibit H3K27me3 methylation mediated by the PRC2 complex. PHF1 regulates also p53/TP53 stability.