Products
Phospho-EIF2S1 (Ser51) antibody antibody
- Product Name
- Phospho-EIF2S1 (Ser51) antibody antibody
- Catalogue No.
- FNab10672
- Size
- 100μg
- Form
- liquid
- Purification
- Protein A+G purification
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- monoclonal
- Isotype
- IgG1
- Clone ID
- 9I7
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- eukaryotic translation initiation factor 2, subunit 1 alpha, 35kDa
- Alternative Names
- EIF 2 antibody, eIF 2 alpha antibody, EIF 2A antibody, EIF 2alpha antibody, EIF2 antibody, EIF2A antibody, EIF2S1/EIF2A antibody, eIF2α antibody
- UniProt ID
- P05198
- Observed MW
- 36 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:1000-1:10000
Validated Images
Hela lysates were subjected to SDS PAGE followed by western blot with FNab10672 at dilution of 1:5000
- Background
- Functions in the early steps of protein synthesis by forming a ternary complex with GTP and initiator tRNA. This complex binds to a 40S ribosomal subunit, followed by mRNA binding to form a 43S preinitiation complex. Junction of the 60S ribosomal subunit to form the 80S initiation complex is preceded by hydrolysis of the GTP bound to eIF-2 and release of an eIF-2-GDP binary complex. In order for eIF-2 to recycle and catalyze another round of initiation, the GDP bound to eIF-2 must exchange with GTP by way of a reaction catalyzed by eIF-2B.
