SOD1 antibody

Synonyms:Superoxide dismutase [Cu-Zn] antibody, Superoxide dismutase 1 antibody, hSod1 antibody
Catalogue No.:FNab10652Reactivity:Human, Mouse, Rat
Host:MouseTested Application:ELISA, WB, IHC, IF
Clonality:monoclonalIsotype:IgG2a
  • SPECIFICATIONS
Product Name
SOD1 antibody
Catalogue No.
FNab10652
Size
100μg
Form
liquid
Purification
Protein A+G purification
Purity
≥95% as determined by SDS-PAGE
Clonality
monoclonal
Isotype
IgG2a
Clone ID
1H8
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
superoxide dismutase 1, soluble
Alternative Names
Superoxide dismutase [Cu-Zn] antibody, Superoxide dismutase 1 antibody, hSod1 antibody
UniProt ID
P00441
Observed MW
16-20 kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:1000 - 1:5000; IHC: 1:100 - 1:200; IF: 1:50 - 1:200
Validated Images
Various lysates were subjected to SDS PAGE followed by western blot with FNab10652(SOD1 antibody) at dilution of 1:2000
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab10652(SOD1 Antibody) at dilution of 1:200
Background
Superoxide dismutase 1, soluble(amyotrophic lateral sclerosis 1(adult))(SOD1, synonyms: ALS, SOD, ALS1, IPOA) binds copper and zinc ions and is one of two isozymes responsible for destroying free uperoxide radicals in the body. This isozyme is a soluble cytoplasmic protein, acting as a homodimer to convert naturally-occuring but harmful superoxide radicals to molecular oxygen and hydrogen peroxide. The other isozyme is a mitochondrial protein. Mutations in this gene have been implicated as causes of familial amyotrophic lateral sclerosis.