Products
AKR1C2 antibody
- Product Name
- AKR1C2 antibody
- Catalogue No.
- FNab10474
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Aldo-keto reductase family 1 member C2
- Alternative Names
- AKR1C2 antibody, AKR1C-pseudo antibody, BABP antibody, DD antibody, DD-2 antibody
- UniProt ID
- P52895
- Observed MW
- 37 kDa
Application
- Tested Applications
- ELISA, WB, IF
- Recommended dilution
- WB: 1:500-1:2000; IF: 1:50-1:200
Validated Images
A549 cells were subjected to SDS PAGE followed by western blot with FNab10474(AKR1C2 Antibody) at dilution of 1:1000
Immunofluorescent analysis of PC-3 cells using FNab10474(AKR1C2 Antibody) at dilution of 1:50.
- Background
- This gene encodes a member of the aldo/keto reductase superfamily, which consists of more than 40 known enzymes and proteins. These enzymes catalyze the conversion of aldehydes and ketones to their corresponding alcohols using NADH and/or NADPH as cofactors. The enzymes display overlapping but distinct substrate specificity. This enzyme binds bile acid with high affinity, and shows minimal 3-alpha-hydroxysteroid dehydrogenase activity. This gene shares high sequence identity with three other gene members and is clustered with those three genes at chromosome 10p15-p14. Three transcript variants encoding two different isoforms have been found for this gene.
