Products
BACE1 antibody
- Product Name
- BACE1 antibody
- Catalogue No.
- FNab10412
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- beta-site APP-cleaving enzyme 1
- Alternative Names
- BACE antibody, KIAA1149 antibody
- UniProt ID
- P56817
- Observed MW
- 50-55 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
Hela cells were subjected to SDS PAGE followed by western blot with FNab10412(BACE1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat brain using FNab10412(BACE1 antibody) at dilution of 1:100
- Background
- Responsible for the proteolytic processing of the amyloid precursor protein(APP). Cleaves at the N-terminus of the A-beta peptide sequence, between residues 671 and 672 of APP, leads to the generation and extracellular release of beta-cleaved soluble APP, and a corresponding cell-associated C-terminal fragment which is later released by gamma-secretase.
