VAV3 antibody

Synonyms:VAV-3 antibody
Catalogue No.:FNab10378Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
VAV3 antibody
Catalogue No.
FNab10378
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
Guanine nucleotide exchange factor VAV3
Alternative Names
VAV-3 antibody
UniProt ID
Q9UKW4
Observed MW
90-100 kDa
Application
Tested Applications
ELISA, WB
Recommended dilution
WB: 1:500-1:2000
Validated Images
mouse spleen were subjected to SDS PAGE followed by western blot with FNab10378(VAV3 antibody) at dilution of 1:800
Background
This gene is a member of the VAV gene family. The VAV proteins are guanine nucleotide exchange factors (GEFs) for Rho family GTPases that activate pathways leading to actin cytoskeletal rearrangements and transcriptional alterations. This gene product acts as a GEF preferentially for RhoG, RhoA, and to a lesser extent, RAC1, and it associates maximally with the nucleotide-free states of these GTPases. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.