Products
MSH6 antibody
- Product Name
- MSH6 antibody
- Catalogue No.
- FNab10369
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- mutS homolog 6
- Alternative Names
- G/T mismatch binding protein antibody, GTBP antibody, GTMBP antibody, hMSH6 antibody, HNPCC5 antibody, HSAP antibody, MSH6 antibody, MutS alpha 160 kDa subunit antibody, mutS homolog 6 (E. coli) antibody, p160 antibody
- UniProt ID
- P52701
- Observed MW
- 120 kDa, 160 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500 - 1:2000
Validated Images
Hela cells were subjected to SDS PAGE followed by western blot with FNab10369(MSH6 antibody) at dilution of 1:1000
- Background
- This gene encodes a member of the DNA mismatch repair MutS family. In E. coli, the MutS protein helps in the recognition of mismatched nucleotides prior to their repair. A highly conserved region of approximately 150 aa, called the Walker-A adenine nucleotide binding motif, exists in MutS homologs. The encoded protein heterodimerizes with MSH2 to form a mismatch recognition complex that functions as a bidirectional molecular switch that exchanges ADP and ATP as DNA mismatches are bound and dissociated. Mutations in this gene may be associated with hereditary nonpolyposis colon cancer, colorectal cancer, and endometrial cancer. Transcripts variants encoding different isoforms have been described.
