Products
ABCC6 antibody
- Product Name
- ABCC6 antibody
- Catalogue No.
- FNab10348
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- ATP-binding cassette, sub-family C (CFTR/MRP), member 6
- Alternative Names
- ABC34 antibody, ABCC6 antibody, ARA antibody, EST349056 antibody, MLP1 antibody, MOAT E antibody, MOATE antibody, MRP6 antibody, PXE antibody, PXE1 antibody
- UniProt ID
- O95255
- Observed MW
- 165 kDa
Application
- Tested Applications
- ELISA, IHC
- Recommended dilution
- IHC: 1:20-1:200
Validated Images
Immunohistochemistry of paraffin-embedded human kidney slide using FNab10348(ABCC6 Antibody) at dilution of 1:100
- Background
- The ATP-binding cassette transporter 6 (ABCC6) gene, also named as MRP6, is a cellular transmembrane protein transporter and belongs to ATP-binding cassette (ABC) family. ABCC6 is an ATP-dependent transporter contains two ATP-binding domains. It is mainly found in the liver, the proximal tubules of the kidneys and the intestines. ABCC6 is involved in a pathway of extracellular nucleotide metabolism and the regulation of tissue calcification. Mutations of ABCC6 leads to pseudoxanthoma elasticum (PXE) which is a rare autosomal recessive disorder. Mutations of ABCC6 can also lead generalized arterial calcification of infancy-2 (GACI2).
