Products

anti- HDAC8 antibody

FNab10275 Catalogue No.
Synonyms
HD8, HDAC8, HDACL1, histone deacetylase 8, RPD3
Host
Rabbit
Reactivity
Human
Isotype
IgG
Tested Application
ELISA, WB
Product Information
Product Name
anti- HDAC8 antibody
Catalogue No.
FNab10275
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
histone deacetylase 8
Synonyms
HD8, HDAC8, HDACL1, histone deacetylase 8, RPD3
Observed MW
15 kDa, 49 kDa
Application
Tested Application
ELISA, WB
Recommended dilution
WB: 1:500 - 1:2000
Uniprot information
UniProt ID
Q9BY41
Images
Hela cells were subjected to SDS PAGE followed by western blot with FNab10275(HDAC8 antibody) at dilution of 1:1000