Products
HDAC8 antibody
- Product Name
- HDAC8 antibody
- Catalogue No.
- FNab10275
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- histone deacetylase 8
- Alternative Names
- HD8 antibody, HDAC8 antibody, HDACL1 antibody, histone deacetylase 8 antibody, RPD3 antibody
- UniProt ID
- Q9BY41
- Observed MW
- 15 kDa, 49 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500 - 1:2000
Validated Images
Hela cells were subjected to SDS PAGE followed by western blot with FNab10275(HDAC8 antibody) at dilution of 1:1000
- Background
- Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to class I of the histone deacetylase family. It catalyzes the deacetylation of lysine residues in the histone N-terminal tails and represses transcription in large multiprotein complexes with transcriptional co-repressors. Multiple transcript variants encoding different isoforms have been found for this gene.
