Products

anti- PP1A antibody

FNab10274 Catalogue No.
Synonyms
PP-1A, PP1A, PP1alpha, PPP1A, PPP1CA
Host
Rabbit
Reactivity
Human, Mouse
Isotype
IgG
Tested Application
ELISA, WB, IHC
Product Information
Product Name
anti- PP1A antibody
Catalogue No.
FNab10274
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
The protein encoded by this gene is one of the three catalytic subunits of protein phosphatase 1 (PP1). PP1 is a serine/threonine specific protein phosphatase known to be involved in the regulation of a variety of cellular processes, such as cell division, glycogen metabolism, muscle contractility, protein synthesis, and HIV-1 viral transcription. Increased PP1 activity has been observed in the end stage of heart failure. Studies in both human and mice suggest that PP1 is an important regulator of cardiac function. Mouse studies also suggest that PP1 functions as a suppressor of learning and memory. Three alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
protein phosphatase 1, catalytic subunit, alpha isoform
Synonyms
PP-1A, PP1A, PP1alpha, PPP1A, PPP1CA
Observed MW
38kDa
Application
Tested Application
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Uniprot information
UniProt ID
P62136
Images
Immunohistochemistry of paraffin-embedded mouse brain tissue slide using FNab10274 (PP1A Antibody) at dilution of 1:100
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab10274 (PP1A antibody) at dilution of 1:1000