Products

anti- IRF3 antibody

FNab10264 Catalogue No.
Synonyms:
interferon regulatory factor 3, IRF 3, IRF3
Host:
Rabbit
Reactivity:
Human, Mouse, Rat
Isotype:
IgG
Tested Application:
ELISA, WB, IHC
Product Information
Product Name
anti- IRF3 antibody
Catalogue No.
FNab10264
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 24 months (Avoid repeated freeze / thaw cycles.)
Background
This gene encodes a member of the interferon regulatory transcription factor (IRF) family. The encoded protein is found in an inactive cytoplasmic form that upon serine/threonine phosphorylation forms a complex with CREBBP. This complex translocates to the nucleus and activates the transcription of interferons alpha and beta, as well as other interferon-induced genes. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Immunogen Information
Immunogen
interferon regulatory factor 3
Synonyms
interferon regulatory factor 3, IRF 3, IRF3
Observed MW
50-55 kDa
Application
Tested Application
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Uniprot information
UniProt ID
Q14653
Images
Immunohistochemistry of paraffin-embedded human lung cancer using FNab10264(IRF3 antibody) at dilution of 1:50
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab10264(IRF3 antibody) at dilution of 1:1000