Products

anti- TBP antibody

FNab10263 Catalogue No.
Synonyms
GTF2D1, TF2D, TFIID
Host
Rabbit
Reactivity
Human
Isotype
IgG
Tested Application
ELISA, WB, IHC
Product Information
Product Name
anti- TBP antibody
Catalogue No.
FNab10263
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex(PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC(preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.
Immunogen Information
Immunogen
TATA box binding protein
Synonyms
GTF2D1, TF2D, TFIID
Observed MW
37-43kDa
Application
Tested Application
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Uniprot information
UniProt ID
P20226
Images
Immunohistochemistry of paraffin-embedded human breast cancer using FNab10263(TBP antibody) at dilution of 1:100
Hela cells were subjected to SDS PAGE followed by western blot with FNab10263(TBP antibody) at dilution of 1:1000