Products
PIK3R2 antibody
- Product Name
- PIK3R2 antibody
- Catalogue No.
- FNab10160
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Phosphatidylinositol 3-kinase regulatory subunit beta
- Alternative Names
- MPPH antibody, MPPH1 antibody, P85B antibody, p85 antibody, p85-BETA antibody, PIK3R2 antibody, PI3-kinase regulatory subunit beta antibody, PI3K regulatory subunit beta antibody, PI3-kinase subunit p85-beta antibody, PtdIns-3-kinase regulatory subunit p85-beta antibody
- UniProt ID
- O00459
- Observed MW
- 81 kDa, 100 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500-1:2000
Validated Images
Hela cells were subjected to SDS PAGE followed by western blot with FNab10160(PIK3R2 antibody) at dilution of 1:1000
- Background
- Phosphatidylinositol 3-kinase (PI3K) plays an important role in the metabolic actions of insulin and is required for adipogenesis. The PI3K pathway has also been identified as an important player in cancer development and progression. The Class IA PI3K heterodimer, which is composed of a P110 catalytic subunit and a P85 regulatory subunit, is activated upon association of the P85 subunit with upstream adaptor proteins or receptor tyrosine kinases. Mutations in PIK3R1 are implicated in cases of breast cancer and associated to SHORT syndrome.
