Products

anti- SOX2 antibody

FNab10148 Catalogue No.
Synonyms
ANOP3, MCOPS3, SOX2, Transcription factor SOX 2
Host
Mouse
Reactivity
Human, Mouse
Isotype
IgG1
Tested Application
ELISA, WB, IHC
Product Information
Product Name
anti- SOX2 antibody
Catalogue No.
FNab10148
Size
100µg
Form
liquid
Purification
protein A+G purified
Purity
≥95% as determined by SDS-PAGE
Host
Mouse
Clonality
monoclonal
Isotype
IgG1
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Transcription factor that forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206(By similarity). Critical for early embryogenesis and for embryonic stem cell pluripotency. May function as a switch in neuronal development. Downstream SRRT target that mediates the promotion of neural stem cell self-renewal(By similarity). Keeps neural cells undifferentiated by counteracting the activity of proneural proteins and suppresses neuronal differentiation(By similarity).
Immunogen Information
Immunogen
SRY(sex determining region Y)-box 2
Synonyms
ANOP3, MCOPS3, SOX2, Transcription factor SOX 2
Observed MW
34kd
Application
Tested Application
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:50-1:200
Uniprot information
UniProt ID
P48431
Images
Immunohistochemistry of paraffin-embedded mouse brain tissue using FNab10148(SOX2 Antibody) at dilution of 1:100
MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab10148(SOX2 antibody) at dilution of 1:1000