Products

anti- CAV3 antibody

FNab10145 Catalogue No.
Synonyms
CAV3, caveolin 3, Caveolin-3, LGMD1C, LQT9, M caveolin, VIP 21, VIP21
Host
Rabbit
Reactivity
Human, Mouse
Isotype
IgG
Tested Application
ELISA, WB, IHC
Product Information
Product Name
anti- CAV3 antibody
Catalogue No.
FNab10145
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.
Immunogen Information
Immunogen
caveolin 3
Synonyms
CAV3, caveolin 3, Caveolin-3, LGMD1C, LQT9, M caveolin, VIP 21, VIP21
Observed MW
17kDa
Application
Tested Application
ELISA, WB, IHC
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Uniprot information
UniProt ID
P56539
Images
Immunohistochemistry of paraffin-embedded human heart using FNab10145(CAV3 antibody) at dilution of 1:100
mouse heart were subjected to SDS PAGE followed by western blot with FNab10145(CAV3 antibody) at dilution of 1:1000