Products
CAV3 antibody
- Product Name
- CAV3 antibody
- Catalogue No.
- FNab10145
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- caveolin 3
- Alternative Names
- CAV3 antibody, caveolin 3 antibody, Caveolin-3 antibody, LGMD1C antibody, LQT9 antibody, M caveolin antibody, VIP 21 antibody, VIP21 antibody
- UniProt ID
- P56539
- Observed MW
- 17kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
mouse heart were subjected to SDS PAGE followed by western blot with FNab10145(CAV3 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human heart using FNab10145(CAV3 antibody) at dilution of 1:100
- Background
- This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.
