Products

anti- 4EBP1 antibody

FNab10129 Catalogue No.
Synonyms
4E BP1, 4EBP1, BP 1, eIF4E binding protein 1, EIF4EBP1, PHAS I
Host
Rabbit
Reactivity
Human, Mouse, Rat
Isotype
IgG
Tested Application
ELISA, WB, IHC, IF
Product Information
Product Name
anti- 4EBP1 antibody
Catalogue No.
FNab10129
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Eukaryotic translation initiation factor 4E-binding protein 1(4EBP1), is a member of 4EBPs family, which regulate the translation of a subset of mRNA by competing with eIF4G for binding to eIF4E, thus preventing the assembly of the eIF4F complex. The eIF4F facilitates the recruitment of other translation initiation factors to form the complex and then initiates cap-dependent translation.4EBP1 also mediates the regulation of protein translation by growth factors, hormones and other stimuli that signal through the MAP kinase and mTORC1 pathways. There are three forms of 4EBP1, alpha, beta and gamma.
Immunogen Information
Immunogen
eukaryotic translation initiation factor 4E binding protein 1
Synonyms
4E BP1, 4EBP1, BP 1, eIF4E binding protein 1, EIF4EBP1, PHAS I
Observed MW
17 kDa
Application
Tested Application
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500-1:1000; IHC: 1:50-1:200; IF: 1:50-1:200
Uniprot information
UniProt ID
Q13541
Images
Immunohistochemistry of paraffin-embedded human breast cancer slide using FNab10129(4EBP1 Antibody) at dilution of 1:50
MCF7 cells were subjected to SDS PAGE followed by western blot with FNab10129(4EBP1 antibody) at dilution of 1:1000