CASP7 antibody

Synonyms:CASP-7 antibody, CMH-1 antibody, ICE-LAP3 antibody, LICE2 antibody, MCH3 antibody
Catalogue No.:FNab10124Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC, IF
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
CASP7 antibody
Catalogue No.
FNab10124
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
caspase-7
Alternative Names
CASP-7 antibody, CMH-1 antibody, ICE-LAP3 antibody, LICE2 antibody, MCH3 antibody
UniProt ID
P55210
Observed MW
37kDa
Application
Tested Applications
ELISA, WB, IHC, IF
Recommended dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Validated Images
293T cells were subjected to SDS PAGE followed by western blot with FNab10124( CASP7 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat heart using FNab10124(CASP7 antibody) at dilution of 1:100
Immunofluorescent analysis of HeLa cells using FNab10124( CASP7 Antibody).
Background
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. The precursor of the encoded protein is cleaved by caspase 3 and 10, is activated upon cell death stimuli and induces apoptosis. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.