anti- PRKCQ antibody
FNab10092
Catalogue No.
- Synonyms:
- PRKCQ, PRKCT, nPKC-theta, protein kinase C theta
- Host:
- Rabbit
- Reactivity:
- Human
- Isotype:
- IgG
- Tested Application:
- ELISA, IHC
Product Information
- Product Name
- anti- PRKCQ antibody
- Catalogue No.
- FNab10092
- Size
- 100µg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Host
- Rabbit
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
- Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors.
Immunogen Information
- Immunogen
- PRKCQ
- Synonyms
- PRKCQ, PRKCT, nPKC-theta, protein kinase C theta
- Observed MW
- 85 kDa
Application
- Tested Application
- ELISA, IHC
- Recommended dilution
- IHC: 1:50 - 1:200
Uniprot information
- UniProt ID
- Q04759
Images
- Image 1
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Immunohistochemistry of paraffin-embedded human colon cancer using FNab10092(PRKCQ antibody) at dilution of 1:50