Products

anti- PRKCQ antibody

FNab10092 Catalogue No.
Synonyms
PRKCQ, PRKCT, nPKC-theta, protein kinase C theta
Host
Rabbit
Reactivity
Human
Isotype
IgG
Tested Application
ELISA, IHC
Product Information
Product Name
anti- PRKCQ antibody
Catalogue No.
FNab10092
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and the second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC family members also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play a distinct role. The protein encoded by this gene is one of the PKC family members. It is a calcium-independent and phospholipid-dependent protein kinase. This kinase is important for T-cell activation. It is required for the activation of the transcription factors NF-kappaB and AP-1, and may link the T cell receptor (TCR) signaling complex to the activation of the transcription factors.
Immunogen Information
Immunogen
PRKCQ
Synonyms
PRKCQ, PRKCT, nPKC-theta, protein kinase C theta
Observed MW
85 kDa
Application
Tested Application
ELISA, IHC
Recommended dilution
IHC: 1:50 - 1:200
Uniprot information
UniProt ID
Q04759
Images
Immunohistochemistry of paraffin-embedded human colon cancer using FNab10092(PRKCQ antibody) at dilution of 1:50