Products

anti- PTCH1 antibody

FNab10084 Catalogue No.
Synonyms
HPE7, NBCCS, Patched, patched homolog 1, Patched1, Protein patched homolog 1, PTC, PTC1, PTCH, PTCH1, PTCH11
Host
Rabbit
Reactivity
Human, Rat
Isotype
IgG
Tested Application
ELISA, IHC
Product Information
Product Name
anti- PTCH1 antibody
Catalogue No.
FNab10084
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Acts as a receptor for sonic hedgehog(SHH), indian hedgehog(IHH) and desert hedgehog(DHH). Associates with the smoothened protein(SMO) to transduce the hedgehog's proteins signal. Seems to have a tumor suppressor function, as inactivation of this protein is probably a necessary, if not sufficient step for tumorigenesis.
Immunogen Information
Immunogen
patched homolog 1
Synonyms
HPE7, NBCCS, Patched, patched homolog 1, Patched1, Protein patched homolog 1, PTC, PTC1, PTCH, PTCH1, PTCH11
Observed MW
161 kDa
Application
Tested Application
ELISA, IHC
Recommended dilution
IHC: 1:20-1:200
Uniprot information
UniProt ID
Q13635
Images
Immunohistochemistry of paraffin-embedded human colon cancer using FNab10084(PTCH1 antibody) at dilution of 1:50