Products
MAP3K1 antibody
- Product Name
- MAP3K1 antibody
- Catalogue No.
- FNab10071
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- mitogen-activated protein kinase kinase kinase 1
- Alternative Names
- MAP3K1 antibody, MAPK/ERK kinase kinase 1 antibody, MAPKKK1 antibody, MEK kinase 1 antibody, MEKK antibody, MEKK 1 antibody, MEKK1 antibody
- UniProt ID
- Q13233
- Observed MW
- 164 kDa
Application
- Tested Applications
- ELISA, IHC
- Recommended dilution
- IHC: 1:20-1:200
Validated Images
Immunohistochemistry of paraffin-embedded human colon cancer using FNab10071( MAP3K1 Antibody) at dilution of 1:100
- Background
- MAP3K1, also named as MAPKKK1, MEKK and MEKK1, belongs to the protein kinase superfamily, STE Ser/Thr protein kinase family and MAP kinase kinase kinase subfamily. MAP3K1 is a component of a protein kinase signal transduction cascade. MAP3K1 activates the ERK and JNK kinase pathways by phosphorylation of MAP2K1 and MAP2K4. It activates CHUK and IKBKB, the central protein kinases of the NF-kappa-B pathway. It catalyzes the reaction: ATP + a protein = ADP + a phosphoprotein.
