HepG2 cells tissue were subjected to SDS PAGE followed by western blot with FNab10049(NPC2 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney cancer tissue slide using FNab10049( NPC2 Antibody) at dilution of 1:200
Background
This gene encodes a protein containing a lipid recognition domain. The encoded protein may function in regulating the transport of cholesterol through the late endosomal/lysosomal system. Mutations in this gene have been associated with Niemann-Pick disease, type C2 and frontal lobe atrophy.