Products

anti- SKP1 antibody

FNab10039 Catalogue No.
Synonyms
EMC19, OCP2, SKP1A, TCEB1L
Host
Rabbit
Reactivity
Human, Rat
Isotype
IgG
Tested Application
ELISA, WB, IHC
Product Information
Product Name
anti- SKP1 antibody
Catalogue No.
FNab10039
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.
Immunogen Information
Immunogen
S-phase kinase-associated protein 1
Synonyms
EMC19, OCP2, SKP1A, TCEB1L
Observed MW
19 kDa
Application
Tested Application
ELISA, WB, IHC
Recommended dilution
WB: 1:200 - 1:2000; IHC: 1:50 - 1:200
Uniprot information
UniProt ID
P63208
Images
Immunohistochemistry of paraffin-embedded rat testis using FNab10039(SKP1 antibody) at dilution of 1:100
A549 cells were subjected to SDS PAGE followed by western blot with FNab10039(SKP1 antibody) at dilution of 1:1000