Products

SKP1 antibody

Synonyms:EMC19 antibody, OCP2 antibody, SKP1A antibody, TCEB1L antibody
Catalogue No.:FNab10039Reativity:Human, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
SKP1 antibody
Catalogue No.
FNab10039
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
S-phase kinase-associated protein 1
Alternative Names
EMC19 antibody, OCP2 antibody, SKP1A antibody, TCEB1L antibody
UniProt ID
P63208
Observed MW
19 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:200 - 1:2000; IHC: 1:50 - 1:200
Validated Images
A549 cells were subjected to SDS PAGE followed by western blot with FNab10039(SKP1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat testis using FNab10039(SKP1 antibody) at dilution of 1:100
Background
This gene encodes a component of SCF complexes, which are composed of this protein, cullin 1, a ring-box protein, and one member of the F-box family of proteins. This protein binds directly to the F-box motif found in F-box proteins. SCF complexes are involved in the regulated ubiquitination of specific protein substrates, which targets them for degradation by the proteosome. Specific F-box proteins recognize different target protein(s), and many specific SCF substrates have been identified including regulators of cell cycle progression and development. Studies have also characterized the protein as an RNA polymerase II elongation factor. Alternative splicing of this gene results in two transcript variants. A related pseudogene has been identified on chromosome 7.