Products

anti- Endoglin/CD105 antibody

FNab10035 Catalogue No.
Synonyms
CD105, END, Endoglin, ENG, FLJ41744, HHT1, ORW, ORW1
Host
Rabbit
Reactivity
Human
Isotype
IgG
Tested Application
ELISA, WB
Product Information
Product Name
anti- Endoglin/CD105 antibody
Catalogue No.
FNab10035
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
This gene encodes a homodimeric transmembrane protein which is a major glycoprotein of the vascular endothelium. This protein is a component of the transforming growth factor beta receptor complex and it binds to the beta1 and beta3 peptides with high affinity. Mutations in this gene cause hereditary hemorrhagic telangiectasia, also known as Osler-Rendu-Weber syndrome 1, an autosomal dominant multisystemic vascular dysplasia. This gene may also be involved in preeclampsia and several types of cancer. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Immunogen Information
Immunogen
endoglin
Synonyms
CD105, END, Endoglin, ENG, FLJ41744, HHT1, ORW, ORW1
Observed MW
50 kDa, 67 kDa
Application
Tested Application
ELISA, WB
Recommended dilution
WB: 1:200-1:2000
Uniprot information
UniProt ID
P17813
Images
MCF-7 cells were subjected to SDS PAGE followed by western blot with FNab10035(ENG antibody) at dilution of 1:1000