FES antibody

Synonyms:FPS antibody, Feline sarcoma/Fujinami avian sarcoma oncogene homolog antibody, Proto-oncogene c-Fes antibody, Proto-oncogene c-Fps antibody, FES antibody, p93c-fes antibody
Catalogue No.:FNab10031Reactivity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
FES antibody
Catalogue No.
FNab10031
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
Tyrosine-protein kinase Fes/Fps
Alternative Names
FPS antibody, Feline sarcoma/Fujinami avian sarcoma oncogene homolog antibody, Proto-oncogene c-Fes antibody, Proto-oncogene c-Fps antibody, FES antibody, p93c-fes antibody
UniProt ID
P07332
Observed MW
98 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:500-1:2000; IHC: 1:50-1:500
Validated Images
mouse brain were subjected to SDS PAGE followed by western blot with FNab10031(FES antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat liver using FNab10031(FES antibody) at dilution of 1:100
Background
This gene encodes the human cellular counterpart of a feline sarcoma retrovirus protein with transforming capabilities. The gene product has tyrosine-specific protein kinase activity and that activity is required for maintenance of cellular transformation. Its chromosomal location has linked it to a specific translocation event identified in patients with acute promyelocytic leukemia but it is also involved in normal hematopoiesis as well as growth factor and cytokine receptor signaling. Alternative splicing results in multiple variants encoding different isoforms.