Products
MX1 antibody
- Product Name
- MX1 antibody
- Catalogue No.
- FNab09996
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- Myxovirus resistance protein 1
- Alternative Names
- IFI 78K antibody, IFI78 antibody, Interferon induced protein p78 antibody, MX antibody, MX1 antibody, MxA antibody, Myxovirus resistance protein 1 antibody
- UniProt ID
- P20591
- Observed MW
- 76 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab09996(MX1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat kidney slide using FNab09996(MX1 Antibody) at dilution of 1:100
- Background
- Interferon-induced dynamin-like GTPase with antiviral activity against a wide range of RNA viruses and some DNA viruses. Its target viruses include negative-stranded RNA viruses and HBV through binding and inactivation of their ribonucleocapsid. May also antagonize reoviridae and asfarviridae replication. Inhibits thogoto virus(THOV) replication by preventing the nuclear import of viral nucleocapsids. Inhibits La Crosse virus(LACV) replication by sequestering viral nucleoprotein in perinuclear complexes, preventing genome amplification, budding, and egress. Inhibits influenza A virus(IAV) replication by decreasing or delaying NP synthesis and by blocking endocytic traffic of incoming virus particles. Enhances ER stress-mediated cell death after influenza virus infection. May regulate the calcium channel activity of TRPCs.
