Products

anti- CASP14 antibody

FNab09900 Catalogue No.
Synonyms
CASP14, ARCI12, caspase-14
Host
Rabbit
Reactivity
Human, Mouse, Rat
Isotype
IgG
Tested Application
ELISA, WB, IF
Product Information
Product Name
anti- CASP14 antibody
Catalogue No.
FNab09900
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier.
Immunogen Information
Immunogen
CASP14
Synonyms
CASP14, ARCI12, caspase-14
Observed MW
30 kDa
Application
Tested Application
ELISA, WB, IF
Recommended dilution
WB: 1:500 - 1:2000; IF: 1:50 - 1:200
Uniprot information
UniProt ID
P31944
Images
Immunofluorescent analysis of MCF-7 cells using FNab09900( CASP14 antibody) at dilution of 1:100.
293T cells were subjected to SDS PAGE followed by western blot with FNab09900( CASP14 antibody) at dilution of 1:1000