SW480 cells were subjected to SDS PAGE followed by western blot with FNab09867(SLC2A2 Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human liver injury using FNab09867(SLC2A2 Antibody) at dilution of 1:100
Background
GLUT2 is a member of glucose transporters or GLUTs which catalyze the glucose transport across plasma membrane. GLUT2 is selectively expressed in hepatocytes, pancreatic beta cells, and absorptive renal and intestinal epithelial cells. GLUT2 is required to maintain normal glucose homeostasis and normal function and development of the endocrine pancreas. Its absence leads to symptoms characteristic of non-insulin-dependent diabetes mellitus. GLUT2 has 60-70 kDa fully glycosylated matured form and a nonglycosylated form around 38-45 kDa.