Products
GAD1 antibody
- Product Name
- GAD1 antibody
- Catalogue No.
- FNab09843
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- glutamate decarboxylase 1
- Alternative Names
- FLJ45882 antibody, GAD antibody, GAD 67 antibody, GAD1 antibody, GAD67 antibody, Glutamate decarboxylase 1 antibody, SCP antibody
- UniProt ID
- Q99259
- Observed MW
- 67 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:500 - 1:2000
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09843( GAD1 Antibody) at dilution of 1:1000
- Background
- This gene encodes one of several forms of glutamic acid decarboxylase, identified as a major autoantigen in insulin-dependent diabetes. The enzyme encoded is responsible for catalyzing the production of gamma-aminobutyric acid from L-glutamic acid. A pathogenic role for this enzyme has been identified in the human pancreas since it has been identified as an autoantigen and an autoreactive T cell target in insulin-dependent diabetes. This gene may also play a role in the stiff man syndrome. Deficiency in this enzyme has been shown to lead to pyridoxine dependency with seizures. Alternative splicing of this gene results in two products, the predominant 67-kD form and a less-frequent 25-kD form.
