HepG2 cells were subjected to SDS PAGE followed by western blot with FNab09839( NPPA Antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded rat heart tissue slide using FNab09839( NPPA Antibody) at dilution of 1:200
Background
The protein encoded by this gene belongs to the natriuretic peptide family. Natriuretic peptides are implicated in the control of extracellular fluid volume and electrolyte homeostasis. This protein is synthesized as a large precursor (containing a signal peptide), which is processed to release a peptide from the N-terminus with similarity to vasoactive peptide, cardiodilatin, and another peptide from the C-terminus with natriuretic-diuretic activity. Mutations in this gene have been associated with atrial fibrillation familial type 6. This gene is located adjacent to another member of the natriuretic family of peptides on chromosome 1.