Products

anti- Zyxin antibody

FNab09764 Catalogue No.
Synonyms
ESP 2, HED 2, ZYX, zyxin, Zyxin 2
Host
Rabbit
Reactivity
Human
Isotype
IgG
Tested Application
ELISA, WB
Product Information
Product Name
anti- Zyxin antibody
Catalogue No.
FNab09764
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Focal adhesions are actin-rich structures that enable cells to adhere to the extracellular matrix and at which protein complexes involved in signal transduction assemble. Zyxin (ZYX) is a zinc-binding phosphoprotein that concentrates at focal adhesions and along the actin cytoskeleton. Zyxin has an N-terminal proline-rich domain and three LIM domains in its C-terminal half. The proline-rich domain may interact with SH3 domains of proteins involved in signal transduction pathways while the LIM domains are likely involved in protein-protein binding. Zyxin may function as a messenger in the signal transduction pathway that mediates adhesion-stimulated changes in gene expression and may modulate the cytoskeletal organization of actin bundles.
Immunogen Information
Immunogen
zyxin
Synonyms
ESP 2, HED 2, ZYX, zyxin, Zyxin 2
Observed MW
80 kDa
Application
Tested Application
ELISA, WB
Recommended dilution
WB: 1:200-1:2000
Uniprot information
UniProt ID
Q15942
Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab09764 (ZYX antibody) at dilution of 1:1000