Products

anti- ZWILCH antibody

FNab09761 Catalogue No.
Synonyms
FLJ10036, FLJ16343, hZwilch, KNTC1AP, Protein zwilch homolog, ZWILCH
Host
Rabbit
Reactivity
Human, Mouse, Rat
Isotype
IgG
Tested Application
ELISA, WB, IHC
Product Information
Product Name
anti- ZWILCH antibody
Catalogue No.
FNab09761
Size
100µg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Host
Rabbit
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Background
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex (PubMed:15824131) .
Immunogen Information
Immunogen
Zwilch, kinetochore associated, homolog (Drosophila)
Synonyms
FLJ10036, FLJ16343, hZwilch, KNTC1AP, Protein zwilch homolog, ZWILCH
Observed MW
67 kDa
Application
Tested Application
ELISA, WB, IHC
Recommended dilution
WB: 1:200-1:2000; IHC: 1:20-1:200
Uniprot information
UniProt ID
Q9H900
Images
Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab09761 (ZWILCH Antibody) at dilution of 1:50
PC-3 cells were subjected to SDS PAGE followed by western blot with FNab09761 (ZWILCH Antibody) at dilution of 1:500