Products

ZWILCH antibody

Synonyms:FLJ10036 antibody, FLJ16343 antibody, hZwilch antibody, KNTC1AP antibody, Protein zwilch homolog antibody, ZWILCH antibody
Catalogue No.:FNab09761Reativity:Human, Mouse, Rat
Host:RabbitTested Application:ELISA, WB, IHC
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
ZWILCH antibody
Catalogue No.
FNab09761
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
Zwilch, kinetochore associated, homolog(Drosophila)
Alternative Names
FLJ10036 antibody, FLJ16343 antibody, hZwilch antibody, KNTC1AP antibody, Protein zwilch homolog antibody, ZWILCH antibody
UniProt ID
Q9H900
Observed MW
67 kDa
Application
Tested Applications
ELISA, WB, IHC
Recommended dilution
WB: 1:200-1:2000; IHC: 1:20-1:200
Validated Images
PC-3 cells were subjected to SDS PAGE followed by western blot with FNab09761(ZWILCH Antibody) at dilution of 1:500
Immunohistochemistry of paraffin-embedded human colon cancer tissue slide using FNab09761(ZWILCH Antibody) at dilution of 1:50
Background
Essential component of the mitotic checkpoint, which prevents cells from prematurely exiting mitosis. Required for the assembly of the dynein-dynactin and MAD1-MAD2 complexes onto kinetochores. Its function related to the spindle assembly machinery is proposed to depend on its association in the mitotic RZZ complex(PubMed:15824131).