L02 cells were subjected to SDS PAGE followed by western blot with FNab09546(XPA Antibody) at dilution of 1:600
Background
Involved in DNA excision repair. Initiates repair by binding to damaged sites with various affinities, depending on the photoproduct and the transcriptional state of the region. Required for UV-induced CHEK1 phosphorylation and the recruitment of CEP164 to cyclobutane pyrimidine dimmers(CPD), sites of DNA damage after UV irradiation.