Products
WEE2 antibody
- Product Name
- WEE2 antibody
- Catalogue No.
- FNab09506
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- WEE1 homolog 2(S. pombe)
- Alternative Names
- FLJ16107 antibody, WEE1 homolog 2(S. pombe) antibody, Wee1 like protein kinase 1B antibody, Wee1 like protein kinase 2 antibody, WEE1B antibody, Wee1B kinase antibody, WEE2 antibody
- UniProt ID
- P0C1S8
- Observed MW
- 63 kDa
Application
- Tested Applications
- ELISA, WB
- Recommended dilution
- WB: 1:200-1:2000
Validated Images
Jurkat cells were subjected to SDS PAGE followed by western blot with FNab09506(WEE2 antibody) at dilution of 1:500
- Background
- Oocyte-specific protein tyrosine kinase that phosphorylates and inhibits CDK1 and acts as a key regulator of meiosis during both prophase I and metaphase II. Required to maintain meiotic arrest in oocytes during the germinal vesicle(GV) stage, a long period of quiescence at dictyate prophase I, by phosphorylating CDK1 at 'Tyr-15', leading to inhibit CDK1 activity and prevent meiotic reentry. Also required for metaphase II exit during egg activation by phosphorylating CDK1 at 'Tyr-15', to ensure exit from meiosis in oocytes and promote pronuclear formation(By similarity).
