NIH/3T3 cells were subjected to SDS PAGE followed by western blot with FNab09497(WDR5 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human kidney cancer using FNab09497(WDR5 antibody) at dilution of 1:100
Background
This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. This protein contains 7 WD repeats. Alternatively spliced transcript variants encoding the same protein have been identified.