Products
UNC5A antibody
- Product Name
- UNC5A antibody
- Catalogue No.
- FNab09261
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- unc-5 homolog A
- Alternative Names
- FLJ16449 antibody, KIAA1976 antibody, Netrin receptor UNC5A antibody, Protein unc 5 homolog 1 antibody, Protein unc 5 homolog A antibody, unc 5 homolog A(C. elegans) antibody, UNC5A antibody, UNC5H1 antibody
- UniProt ID
- Q6ZN44
- Observed MW
- 93 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500-1:2000; IHC: 1:50-1:500
Validated Images
Hela cells were subjected to SDS PAGE followed by western blot with FNab09261(UNC5A antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human brain using FNab09261(UNC5A antibody) at dilution of 1:100
- Background
- Receptor for netrin required for axon guidance. Functions in the netrin signaling pathway and promotes neurite outgrowth in response to NTN1. Mediates axon repulsion of neuronal growth cones in the developing nervous system in response to netrin. Axon repulsion in growth cones may be mediated by its association with DCC that may trigger signaling for repulsion. It also acts as a dependence receptor required for apoptosis induction when not associated with netrin ligand.
