HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab08918(TRAF3IP1 Antibody) at dilution of 1:300
IP Result of anti-TRAF3IP1 (IP:FNab08918, 3ug; Detection:FNab08918 1:300) with HeLa cells lysate 2000ug.
Immunohistochemistry of paraffin-embedded human breast cancer tissue slide using FNab08918(TRAF3IP1 Antibody) at dilution of 1:50
Background
Plays an inhibitory role on IL13 signaling by binding to IL13RA1. Involved in suppression of IL13-induced STAT6 phosphorylation, transcriptional activity and DNA-binding. Recruits TRAF3 and DISC1 to the microtubules. Involved in kidney development and epithelial morphogenesis. Involved in the regulation of microtubule cytoskeleton organization. Is a negative regulator of microtubule stability, acting through the control of MAP4 levels(PubMed:26487268). Involved in ciliogenesis(By similarity).