Products
TPM3 antibody
- Product Name
- TPM3 antibody
- Catalogue No.
- FNab08890
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- tropomyosin 3
- Alternative Names
- Tropomyosin alpha-3 chain|Gamma-tropomyosin|Tropomyosin-3|Tropomyosin-5 (hTM5)|TPM3 antibody
- UniProt ID
- P06753
- Observed MW
- 37 kDa
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Validated Images
mouse skeletal muscle tissue were subjected to SDS PAGE followed by western blot with FNab08890(TPM3 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse heart using FNab08890(TPM3 antibody) at dilution of 1:50
- Background
- This gene encodes a member of the tropomyosin family of actin-binding proteins. Tropomyosins are dimers of coiled-coil proteins that provide stability to actin filaments and regulate access of other actin-binding proteins. Mutations in this gene result in autosomal dominant nemaline myopathy and other muscle disorders. This locus is involved in translocations with other loci, including anaplastic lymphoma receptor tyrosine kinase (ALK) and neurotrophic tyrosine kinase receptor type 1 (NTRK1), which result in the formation of fusion proteins that act as oncogenes. There are numerous pseudogenes for this gene on different chromosomes. Alternative splicing results in multiple transcript variants.
