Products
TOP2A antibody
- Product Name
- TOP2A antibody
- Catalogue No.
- FNab08867
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- topoisomerase(DNA) II alpha 170kDa
- Alternative Names
- TOP2 antibody
- UniProt ID
- P11388
- Observed MW
- 174 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IF, IP
- Recommended dilution
- WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
HeLa cells were subjected to SDS PAGE followed by western blot with FNab08867(TOP2A Antibody) at dilution of 1:1000
IP Result of anti-TOP2A (IP:FNab08867, 4ug; Detection:FNab08867 1:1000) with HeLa cells lysate 2000ug.
Immunohistochemistry of paraffin-embedded human spleen slide using FNab08867(TOP2A Antibody) at dilution of 1:50
- Background
- Control of topological states of DNA by transient breakage and subsequent rejoining of DNA strands. Topoisomerase II makes double-strand breaks. Essential during mitosis and meiosis for proper segregation of daughter chromosomes. May play a role in regulating the period length of ARNTL/BMAL1 transcriptional oscillation(By similarity).
