Products
TGF-beta 3 antibody
Category:
Research Area:
- SPECIFICATIONS
- Product Name
- TGF-beta 3 antibody
- Catalogue No.
- FNab08640
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- transforming growth factor, beta 3
- Alternative Names
- ARVD antibody, ARVD1 antibody, LDS5 antibody, RNHF antibody, TGF-beta3 antibody
- UniProt ID
- P10600
- Observed MW
- 45KD
Application
- Tested Applications
- ELISA, WB, IHC
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:100
Validated Images
K-937 cells were subjected to SDS PAGE followed by western blot with FNab08640(TGFB3 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded mouse ovary using FNab08640(TGFB3 antibody) at dilution of 1:100
- Background
- This gene encodes a secreted ligand of the TGF-beta (transforming growth factor-beta) superfamily of proteins. Ligands of this family bind various TGF-beta receptors leading to recruitment and activation of SMAD family transcription factors that regulate gene expression. The encoded preproprotein is proteolytically processed to generate a latency-associated peptide (LAP) and a mature peptide, and is found in either a latent form composed of a mature peptide homodimer, a LAP homodimer, and a latent TGF-beta binding protein, or in an active form consisting solely of the mature peptide homodimer. The mature peptide may also form heterodimers with other TGF-beta family members. This protein is involved in embryogenesis and cell differentiation, and may play a role in wound healing. Mutations in this gene are a cause of aortic aneurysms and dissections, as well as familial arrhythmogenic right ventricular dysplasia 1.