Products
TFAM antibody
- Product Name
- TFAM antibody
- Catalogue No.
- FNab08615
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- transcription factor A, mitochondrial
- Alternative Names
- MtTF1 antibody, mtTFA antibody, TCF 6 antibody, TCF6 antibody, TCF6L1 antibody, TCF6L2 antibody, TCF6L3 antibody, TFAM antibody, Transcription factor 6 antibody, Transcription factor 6 like 2 antibody
- UniProt ID
- Q00059
- Observed MW
- 25 kDa
Application
- Tested Applications
- ELISA, WB, IHC, IP
- Recommended dilution
- WB: 1:500-1:3000; IP: 1:500-1:1000; IHC: 1:50-1:500
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab08615(TFAM antibody) at dilution of 1:1000
IP Result of anti-TFAM (IP: FNab08615, 4ug; Detection: FNab08615 1:800) with HEK-293 cells lysate 3000ug.
Immunohistochemistry of paraffin-embedded human kidney slide using FNab08615(TFAM Antibody) at dilution of 1:50
- Background
- Binds to the mitochondrial light strand promoter and functions in mitochondrial transcription regulation. Required for accurate and efficient promoter recognition by the mitochondrial RNA polymerase. Promotes transcription initiation from the HSP1 and the light strand promoter by binding immediately upstream of transcriptional start sites. Is able to unwind DNA. Bends the mitochondrial light strand promoter DNA into a U-turn shape via its HMG boxes. Required for maintenance of normal levels of mitochondrial DNA. May play a role in organizing and compacting mitochondrial DNA.
