Products
SOS1 antibody
- Product Name
- SOS1 antibody
- Catalogue No.
- FNab08118
- Size
- 100μg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
- Immunogen
- son of sevenless homolog 1
- Alternative Names
- SOS1 antibody, GF1 antibody, GGF1 antibody, GINGF antibody, HGF antibody, NS4 antibody, son of sevenless homolog 1 antibody
- UniProt ID
- Q07889
- Observed MW
- 180 kDa
Application
- Tested Applications
- ELISA, WB, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IF: 1:50 - 1:100
Validated Images
Hela cells were subjected to SDS PAGE followed by western blot with FNab08118(SOS1 antibody) at dilution of 1:1000
- Background
- Promotes the exchange of Ras-bound GDP by GTP(PubMed:8493579). Probably by promoting Ras activation, regulates phosphorylation of MAP kinase MAPK3 in response to EGF(PubMed:17339331). Catalytic component of a trimeric complex that participates in transduction of signals from Ras to Rac by promoting the Rac-specific guanine nucleotide exchange factor(GEF) activity(By similarity).
