SIX5 antibody

Synonyms:DMAHP antibody
Catalogue No.:FNab07889Reactivity:Human
Host:RabbitTested Application:ELISA, IHC, WB, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
SIX5 antibody
Catalogue No.
FNab07889
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
SIX homeobox 5
Alternative Names
DMAHP antibody
UniProt ID
Q8N196
Observed MW
100-105 kDa
Application
Tested Applications
ELISA, IHC, WB, IP
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
Y79 cells were subjected to SDS PAGE followed by western blot with FNab07889(SIX5 Antibody) at dilution of 1:600
IP Result of anti-SIX5 (IP:FNab07889, 4ug; Detection:FNab07889 1:300) with Y79 cells lysate 2000ug.
Immunohistochemistry of paraffin-embedded human kidney tissue slide using FNab07889(SIX5 Antibody) at dilution of 1:200
Background
Transcription factor that is thought to be involved in regulation of organogenesis. May be involved in determination and maintenance of retina formation. Binds a 5'-GGTGTCAG-3' motif present in the ARE regulatory element of ATP1A1. Binds a 5'-TCA[AG][AG]TTNC-3' motif present in the MEF3 element in the myogenin promoter, and in the IGFBP5 promoter(By similarity). Thought to be regulated by association with Dach and Eya proteins, and seems to be coactivated by EYA1, EYA2 and EYA3(By similarity).