anti- SF3B2 antibody
FNab07778
Catalogue No.
- Synonyms:
- SAP145
- Host:
- Rabbit
- Reactivity:
- Human, Mouse, Rat
- Isotype:
- IgG
- Tested Application:
- ELISA, WB, IHC, IF
Product Information
- Product Name
- anti- SF3B2 antibody
- Catalogue No.
- FNab07778
- Size
- 100µg
- Form
- liquid
- Purification
- Immunogen affinity purified
- Purity
- ≥95% as determined by SDS-PAGE
- Host
- Rabbit
- Clonality
- polyclonal
- Isotype
- IgG
- Storage
- PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20℃ for 12 months (Avoid repeated freeze / thaw cycles.)
Background
- This gene encodes subunit 2 of the splicing factor 3b protein complex. Splicing factor 3b, together with splicing factor 3a and a 12S RNA unit, forms the U2 small nuclear ribonucleoproteins complex (U2 snRNP) . The splicing factor 3b/3a complex binds pre-mRNA upstream of the intron's branch site in a sequence-independent manner and may anchor the U2 snRNP to the pre-mRNA. Splicing factor 3b is also a component of the minor U12-type spliceosome. Subunit 2 associates with pre-mRNA upstream of the branch site at the anchoring site. Subunit 2 also interacts directly with subunit 4 of the splicing factor 3b complex. Subunit 2 is a highly hydrophilic protein with a proline-rich N-terminus and a glutamate-rich stretch in the C-terminus.
Immunogen Information
- Immunogen
- splicing factor 3b, subunit 2, 145kDa
- Synonyms
- SAP145
- Observed MW
- 140 kDa
Application
- Tested Application
- ELISA, WB, IHC, IF
- Recommended dilution
- WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Uniprot information
- UniProt ID
- Q13435
Images
- Image 1
-
Immunohistochemistry of paraffin-embedded rat kidney using FNab07778 (SF3B2 antibody) at dilution of 1:100
- Image 4
-
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab07778 (SF3B2 antibody) at dilution of 1:1000