K-562 cells were subjected to SDS PAGE followed by western blot with FNab07547(RYBP antibody) at dilution of 1:500
IP Result of anti-RYBP (IP:FNab07547, 4ug; Detection:FNab07547 1:300) with mouse spleen tissue lysate 4000ug.
Background
Inhibits ubiquitination and subsequent degradation of TP53, and thereby plays a role in regulating transcription of TP53 target genes. May be implicated in the regulation of the transcription as a repressor of the transcriptional activity of E4TF1. May bind to DNA. Promotes apoptosis.