HeLa cells were subjected to SDS PAGE followed by western blot with FNab07492(RRM1 antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human stomach using FNab07492( RRM1 Antibody) at dilution of 1:100
Background
This gene encodes the large and catalytic subunit of ribonucleotide reductase, an enzyme essential for the conversion of ribonucleotides into deoxyribonucleotides. A pool of available deoxyribonucleotides is important for DNA replication during S phase of the cell cycle as well as multiple DNA repair processes. Alternative splicing results in multiple transcript variants.