RNase T2 antibody

Synonyms:Ribonuclease 6 antibody, Ribonuclease T2 antibody, RNASE6PL antibody, RNASET2 antibody
Catalogue No.:FNab07324Reactivity:Human, Mouse
Host:RabbitTested Application:ELISA, IHC, IF, WB, IP
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
RNase T2 antibody
Catalogue No.
FNab07324
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
ribonuclease T2
Alternative Names
Ribonuclease 6 antibody, Ribonuclease T2 antibody, RNASE6PL antibody, RNASET2 antibody
UniProt ID
O00584
Observed MW
29 kDa
Application
Tested Applications
ELISA, IHC, IF, WB, IP
Recommended dilution
WB: 1:500-1:1000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Validated Images
HEK-293 cells were subjected to SDS PAGE followed by western blot with FNab07324(RNASET2 antibody) at dilution of 1:500
IP Result of anti-RNase T2 (IP:FNab07324, 4ug; Detection:FNab07324 1:300) with BxPC-3 cells lysate 4000ug.
Immunohistochemistry of paraffin-embedded human pancreas cancer using FNab07324(RNASET2 antibody) at dilution of 1:100
Background
RNASET2(Ribonuclease T2) is also named as RNASE6PL(Ribonuclease 6) and belongs to the RNase T2 family. It is a unique member of the growing family of tumor-antagonizing genes and behaves as a class II tumor suppressor and abolish the tumorigenic potential of an ovarian cancer-derived cell line. This protein has 2 isoforms produced by alternative splicing. Both mildly glycosylated (ranging from38 to 45 kDa) and highly glycosylated forms (ranging from 50 to 80 kDa) of human tumor suppressor protein RNASET2 can be detected in immunoblotting