RMI1 antibody

Synonyms:C9orf76 antibody
Catalogue No.:FNab07321Reactivity:Human
Host:RabbitTested Application:ELISA, IHC, IP, WB
Clonality:polyclonalIsotype:IgG
  • SPECIFICATIONS
Product Name
RMI1 antibody
Catalogue No.
FNab07321
Size
100μg
Form
liquid
Purification
Immunogen affinity purified
Purity
≥95% as determined by SDS-PAGE
Clonality
polyclonal
Isotype
IgG
Storage
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20℃ for 12 months(Avoid repeated freeze / thaw cycles.)
Immunogen
Immunogen
RMI1, RecQ mediated genome instability 1, homolog
Alternative Names
C9orf76 antibody
UniProt ID
Q9H9A7
Observed MW
75 kDa
Application
Tested Applications
ELISA, IHC, IP, WB
Recommended dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Validated Images
HepG2 cells were subjected to SDS PAGE followed by western blot with FNab07321(RMI1 antibody) at dilution of 1:500
IP Result of anti-RMI1 (IP:FNab07321, 3ug; Detection:FNab07321 1:1500) with HeLa cells lysate 3800ug.
Immunohistochemistry of paraffin-embedded human gliomas using FNab07321(RMI1 antibody) at dilution of 1:100
Background
Essential component of the RMI complex, a complex that plays an important role in the processing of homologous recombination intermediates to limit DNA crossover formation in cells. Promotes TOP3A binding to double Holliday junctions(DHJ) and hence stimulates TOP3A-mediated dissolution. Required for BLM phosphorylation during mitosis. Within the BLM complex, required for BLM and TOP3A stability.