HeLa cells were subjected to SDS PAGE followed by western blot with FNab07281(RHOA antibody) at dilution of 1:1000
Immunohistochemistry of paraffin-embedded human gastric cancer tissue slide using FNab07281( RHOA Antibody) at dilution of 1:100
Background
This gene encodes a member of the Rho family of small GTPases, which cycle between inactive GDP-bound and active GTP-bound states and function as molecular switches in signal transduction cascades. Rho proteins promote reorganization of the actin cytoskeleton and regulate cell shape, attachment, and motility. Overexpression of this gene is associated with tumor cell proliferation and metastasis. Multiple alternatively spliced variants have been identified.